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This threshold was set given its importance from a clinical rather than a statistical viewpoint, and since it falls within the range normally accepted for this type of study [37]

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IV zinc differs in several ways: Delivered directly into circulation Avoids gastrointestinal irritation Allows for predictable absorption Can be combined with hydration and other supportive nutrients IV administration may be considered when oral intake is insufficient, poorly tolerated, or ineffective in meeting short-term physiological demand

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