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This suggested a direct function of GSTs in the active clearance of the MP from the perireceptor environment in this developmental period where a high sensitivity to the MP must be maintained to ensure survival 11,13 .We further developed an ex vivo headspace gas-chromatography method to measure MP metabolism in quasi physiological exposure conditions, i.e., by suing intact OM fresh explants in contact with MP on gaseous form

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While we didnt see phase 3 insulin sensitivity data, its clear that it profoundly reduces that just based on phase 2 data