The weight loss difference between liraglutide and phentermine is smaller than with semaglutide or tirzepatide, which means the other factors, cost, side effects, duration of treatment, and long-term outcomes, carry more relative weight in the decision
For example, the expression of ALOX15 is mediated by spermidine/spermine N1-acetyltransferase 1, a tumor protein p53 (TP53) target gene, and is involved in TP53-mediated ferroptosis (Ou et al., 2016)
Feb 2018;25(2):269-275
They have also been known to increase concentration, memory, and energy levels, support weight loss by improving metabolism, help boost the immune system, have been shown to improve sleep and can help stop some types of hair loss