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For example, other drug makers might pursue this approach going forward, compared to the more rigorous FDA approval pathway

The third family, IGF-1 LR3, skips the GH-signaling step entirely, binding directly to the IGF-1 receptor on muscle tissue and activating the PI3K/Akt and MAPK pathways tied to cell growth

No one should stop a prescribed medicine on their own because of B12 concerns, but it may be reasonable to ask whether monitoring is needed