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This reflects the massmarket scale of obesity and diabetes, where oral options could materially expand access, persistence, and earlier therapy initiation or continuation of treatment for patients moving from injectable to orals, Campbell said
In particular, semaglutide was specifically under investigation by regulators, including the EMA and the FDA, because of a series of reports and pharmacovigilance studies on suicidal or self-harming thoughts [141, 142]
For further information, see the NHS medicines pages for semaglutide, liraglutide, and dulaglutide, and the European Medicines Agency (EMA) European Public Assessment Reports (EPARs) for these agents
Future attention to disease prevention could accommodate approaches beyond conventional glucose and weight control that consider how inflammatory, infective and environmental stress factors contribute to type 2 diabetes
