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In SUSTAIN 6, a placebo-corrected heart rate increase of 2.75 beats per minute (bpm) was observed for semaglutide 0.5 mg, and 3.2 bpm for the 1.0 mg dosage (97)
Nineteen of those WLs concern OTC products: eight letters were for unapproved sunscreen dosage forms,10 five letters were for unapproved ophthalmic products, and six letters were for unapproved external analgesics intended to be used prior to sensitive cosmetic procedures
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