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Now, enter the GLP-1 receptor agonists (GLP-1 RAs)
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Paraesthesia (pins and needles) in the hands and feet often improves within two to four weeks, though complete resolution may take several months
While tirzepatide's primary therapeutic targets relate to metabolic function, receptor activation in these brain areas could potentially influence mood pathways, though human evidence for direct effects remains limited and inconclusive
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