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*Correspondence: Daoyu Guo, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
it introduces an uncontrolled variable into any protocol relying on precise dosing calculations
Evidence supporting the link between hypermethioninemia and liver injury In rabbit, intravenous administration of Met (121 mg/kg/d) could lead to a blockage of bile flow and jaundice (33), and these liver damages are similar to parenteral nutrition cholestasis (33)
This work would not have been possible without the input from Darren Edwards and our excellent compound (Alex Cookson, Kirsty Cookson, & Desiree Zeller) and data management teams (James Burkinshaw & Kashish Sharma).
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