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Novo Nordisk reported the results from the STEP 1 extension trial on the impact of treatment withdrawal, which found that one year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained two-thirds of their prior weight loss
The key question in STRIDE was whether semaglutide can change the trajectory of disease in individuals with type 2 diabetes and PAD who are identified at the earliest symptomatic stage of PAD
It is important to stress that it is completely normal to feel some hunger while on Mounjaro, especially on lower doses
The sub-therapeutic starting dose exists for a reason
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