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Rebora A, Delmonte S, Parodi A
Cardiovascular and Renal Outcomes With Efpeglenatide in Type 2 Diabetes
In most published and exploratory work, BPC-157 is evaluated alongside markers such as inflammatory mediators, vascular changes, or structural proteins
ER stress results in the activation of the unfolded protein response (UPR) pathway, which if persistent, morphs into terminal UPR, which can promote upregulation of genes involved in iron uptake, storage, and utilization, and the inhibition of genes involved in the regulation of antioxidant defense and fatty acid metabolism, sensitizing cells to ferroptosis [99-102]
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