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The product is likewise indicated for increased physiologic demand (pregnancy, thyrotoxicosis, chronic hemorrhage), for drug-induced depletion, and for select neurologic or hematologic disorders in which B12 plays a pivotal metabolic role
Timing matters too
One study, for instance, notes that people who are overweight or obese appear to have lower levels of vitamin B12 than those with a body mass index (BMI) that falls within the range considered to be normal. People who took vitamin B12 supplements of their own volition gained between 2.5 and 17 fewer pounds (1.27.7 kg) over ten years compared to those who did not take any form of supplementation with this vitamin
Andersson, Emmanuel Shapira, Biochemical and clinical response to hydroxocobalamin versus cyanocobalamin treatment in patients with methylmalonic acidemia and homocystinuria (cblC), The Journal of Pediatrics, Volume 132, Issue 1, January 1998, Pages 121-124, ISSN 0022-3476, Okuda K, Yashima K, Kitazaki T, Takara I
