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Mechanisms that regulate DPP4 gene transcription and enzymatic activity are not fully understood so far and may be dependent on the studied cell type
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doi 10.1073/pnas.96.4.1569 62 DaCambraMPYustaBSumner-SmithMCriviciADruckerDJBrubakerPL
If these side effects become too disruptive, it may be necessary to reconsider the medication regimen
Diabetic retinopathy in people with diabetes In semaglutide studies in diabetes, early worsening of diabetic retinopathy complications was observed, likely related to rapid glucose improvement rather than a direct drug effect
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