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An epidural catheter is less invasive and has a lower complication rate (infection and bleeding).45 The prophylactic use of recombinant Factor VIIa, fresh frozen plasma, and desmopressin prior to the placement of intraparenchymal monitoring is an option for reducing the bleeding risk to grade 3.4850 Coagulopathy INR prolongation is a characteristic that presents in all cases of ALF, according to its definition, but importantly, associated bleeding is rare (5-10%)

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It is vital to choose a reputable , licensed provider who follows proper injection protocols and maintains high hygiene standards to reduce the risk of serious complications

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