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2.5.7.5 R07837195 RO7837195 is a p40xTL1A bispecific antibody developed through a Roche-Pfizer collaboration that simultaneously targets IL-12/IL-23 (via the p40 subunit) and TL1A pathways, currently being evaluated in the Phase IIb SUNCREST trial (NCT06979336) which employs a multicenter, double-blind, placebo-controlled design with a 12-week induction Phase followed by a 40-week active treatment extension in approximately 224 participants across five dosing arms