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Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial
Central appetite suppression
A recent integrative study combining magnetic resonance imaging (MRI), quantitative susceptibility mapping (QSM), and regional gene expression profiling has revealed significantly elevated cortical iron accumulation in PD (37)
These effects are mediated by the activation of the PI3K-HIF-1 signaling axis by SUCNR1 [362]
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