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Key Takeaways: GLP-1 agonists, such as Ozempic and Wegovy, carry a black box warning due to an association with thyroid cancer, particularly in individuals with RET gene mutations

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In short: TRIUMPH-3 shows retatrutide can be used safely in a cardiovascular disease population without signal of harm, but the question of whether it actively reduces heart attacks and strokes remains open until TRIUMPH-Outcomes reports

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