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Overall, they found that individuals using GLP-1s were 10% less likely to visit the emergency room, 14% less likely to be hospitalized, and around 13% less likely to need a nerve block procedure or receive a triptan prescription than those taking topiramate
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The risk has been reported in trials, with accumulating, rare instances of optic nerve damage among users, particularly as GLP-1 drugs originally developed for type 2 diabetes are being increasingly used off-label for weight management
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