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Enhancing Satiety and Reducing Food Cravings Since semaglutide helps someone feel full for longer and decreases hunger cues, many people who take this drug report less food noise, obsessive thoughts about food, and fewer cravings for hyperpalatable food, like french fries or ice cream

Ex vivo assessments of hippocampal fatty acid -oxidation in acute brain slices from young ApoE4 knock-in mice reveal impaired lipid catabolism coupled with marked lipid accumulation, indicative of a sustained deficit in -oxidative metabolism (Qi et al., 2021b)

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BMJ 368, m1086