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The mean hides the spread: 78.7% of that arm lost 5% of body weight, 55.1% lost 10% and 31.0% lost 15%
the TRIUMPH trials are ongoing, with full data needed before any regulatory submission to the MHRA or EMA can take place
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In contrast, other agonists that exhibit stable open TM6/ECL3/TM7/TM1 conformations, including exendin-P5, are correlated with a bias towards G protein-mediated signalling
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