Reviews clinical and preclinical evidence for GHK-Cus role in collagen synthesis, wound healing, anti-inflammatory regulation, and skin architecture improvement
Before human translation, essential parameters to define: optimal dosing, infusion/administration route, frequency, biomarkers to monitor (senescent cell burden, inflammatory cytokines, organ function), long-term follow-up for adverse outcomes (especially tumour risk)
It represents the biologically active fragment of the larger endogenous Body Protection Compound (BPC, MW ~40,000 Da), the smallest sequence retaining BPCs full biological activity profile
Modulates inflammatory and tissue remodelling responses