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In one 6-month study published in 2001, fifty women were given a fixed dose of TSH-suppressive L-T(4) therapy
13 MELANOSIS Diagnosis Dark (usually black) flat, smooth, 5- to 25-mm patch Asymmetric or angular configuration Located primarily on nonkeratinizing (mucosal) tissue Unchanging appearance (if patient has previously been aware of the lesion) Incisional biopsy to rule out dysplasia and malignancy Dermoscopy of lentiginosis requires an experienced dermoscopist, and there is no one pattern
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