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CLINICAL TRIAL EVIDENCE FOR DUAL GLP-1/GLUCAGON RAs AND TRIPLE AGONISTS IN MASH Survodutide Survodutide, a weekly dual GLP-1/GCG agonist, was assessed in a phase 2 dose-finding trial (NCT04771273) including 293 individuals with histologically confirmed MASH and fibrosis stages F1-F3 [46]
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In fact, the appetite suppression can be so strong that users under-eat, losing muscle mass along with fat, developing micronutrient deficiencies, and setting themselves up for metabolic adaptation that stalls weight loss
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