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Veiga JP, Nunes R, Konopleva M, Sallan SE, Sporn MB, Nadler LM, Andreeff M , Cardoso AA
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Clinical, endocrine and metabolic effects of metformin vs N-acetyl-cysteine in women with polycystic ovary syndrome
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The key anti-inflammatory effects included: Modulation of macrophage activation states Decreased reactive nitrogen species production Reduced efferocytotic activity in treated cells Lower expression of pro-inflammatory mediators Research on corneal injuries found TB-500 suppressed multiple inflammatory mediators while maintaining bacterial clearance when combined with antibiotics
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