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Specifically, downregulation of the neuronal lactate transporter MCT2 or the astroglial lactate transporter MCT4 in the rat barrel cortex abolished the lactate rise in response to sensory stimulation
The injection reaches its maintenance dose of 2.4mg weekly over a similar period but via a different set of dose steps
These modifications dont change how semaglutide activates GLP-1 receptors or its therapeutic effects
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