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Hypoxia induces an ECSC stem-like state by demethylation of SOX2 mRNA Here, we found that the hypoxia-induced demethylase ALKBH5 promoted SOX2 expression and the stem-like state of ECSCs

The FDA warned another Indian facility for widespread data integrity failures, inadequate manufacturing and cleaning validation, insufficient microbiological testing, and inaccurate drug listings

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however, no maternal or fetal complications have been associated with doses that are recommended during pregnancy, and appropriate treatment should not be withheld from pregnant women with vitamin B12 responsive anemias