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Animal studies involving both GH-deficient and non-GH-deficient mice have shown that twice-daily ipamorelin injections lead to significant increases in body weight (15.3% and 16.9% respectively) [8] and stimulate GH secretion, which is lipolytic [9]

As intracellular GSH is exhausted, the GSH synthesis system will be activated accordingly, which would weaken the efficacy of GSH exhaustion-based cancer therapies in long-term treatment (Xiong et al., 2021)

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There is a risk of mild diarrhoea, upset stomach, nausea, a feeling of pain and warm sensation at the site of the injection, a feeling or a sense of being swollen over the entire body, headache and joint pain