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3 , e373 (2012)

15-20% On average, people on semaglutide or tirzeparide lose 15-20% of their weight in a year* *In a 68- and 72-week clinical trial examining Semaglutide (2.4 mg) and Tirzepatide (15 mg) in patients without diabetes and with a BMI 30, or BMI 27 with a weight-related condition, the average weight loss was 15% and 20%, respectively, when combined with dietary and exercise modifications

Adequate hydration and dietary fiber intake help manage this side effect

Because semaglutide delays gastric emptying, food may remain in the abdomen beyond fasting guidelines, placing patients at risk for this serious complication