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After LPS stimulation, the expression of GLP-1R was significantly increased compared with that of the sham group (Fig
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This article reviews current evidence, potential mechanisms, and practical guidance for patients and healthcare providers
The authors recommend providing in-depth counselling and possibly slower titration of GLP-1 RAs during initiation in these groups, particularly those who are known to have discontinued metformin previously, in order to decrease discontinuation rates
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