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The hypothalamus releases natural GHRH to stimulate the pituitary directly, while a separate ghrelin pathway modulates the amplitude and timing of each secretory pulse
Compared to Growth Hormone Secretagogues: Peptides like ipamorelin and CJC-1295/ipamorelin combinations work by stimulating natural growth hormone release, producing IGF-1 elevation and the associated growth hormone effects
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It belongs to a class of compounds known as metallopeptides, so its research relevance is directly tied to its ability to bind and transport copper at the cellular level
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