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D57 (CTR) and D254 (G), were predicted protonated, however, visual inspection did not support this prediction because of their solvent-exposed location and, therefore, were modelled in the anionic side chain form
A., Oliveira, A
Patients with known chronic conditions such as liver disease, kidney disease, or previous cancershould ensure their healthcare team is aware of elevated B12 results, as this may influence monitoring strategies or treatment decisions
Modern pharmacology shows that HDTCM contains a variety of potential anti-AD ingredients, and their mechanism of action involves multiple targets and pathways (Han et al., 2016
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