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Can have a rapid onset of action, often producing effects within minutes to an hour after administration, which can be advantageous for spontaneous sexual activity

Rodent models metabolize many peptides 25 times faster than primates due to higher metabolic rate and plasma peptidase activity

Bondeson DP, Smith BE, Burslem GM, Buhimschi AD, Hines J, Jaime-Figueroa S, Wang J, Hamman BD, Ishchenko A, Crews CM (2018) Lessons in PROTAC design from selective degradation with a promiscuous warhead

A study that poses an important methodological issue on the possible detection bias induced by glucagon-like peptide 1 receptor agonist treatment