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Applying to completely dry skin reduces penetration and leaves more product sitting on the surface where it can't work
GLP-1 effects include slowing gastric emptying, increasing satiety, as well as cardioprotective effects ( via inducing osteoblast activity and reduction of bone resorption via inhibition of osteoclasts ( Figure 1 )
Tirzepatide, a dual GIP/GLP-1 agonist, showed up to 20.9% average weight loss in SURMOUNT-1 at 72 weeks
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