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It is produced within the body and found in high concentrations in several tissues

A 2025 European Journal of Clinical Nutrition commentary on the NICE guideline argued that the diagnostic threshold and clinical awareness still need to be tightened further, especially around pernicious anaemia, which is still under-recognised in primary care

Recently, an abundance of experimental research was conducted, especially on animals, to discover how the gut microbiota influences GBA (27)

Each component plays a distinct role: choline and methionine are involved in the transport and breakdown of fats in the liver, and inositol participates in cell signaling