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Trial data have shown decreases in serious cardiovascular complications, including cardiovascular mortality, nonlethal heart attacks, and nonfatal cerebrovascular accidents, among individuals with type 2 diabetes and pre-existing cardiovascular pathology or high cardiovascular risk [3,5,13,14,37]
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For example, certain FTO genotypes correlate with baseline obesity risk and potentially differential weight loss trajectories on GLP-1 agonists
At the conclusion of the 68 week study, the treatment group lost about 15% body weight (37 lb for a 250 lb individual)
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