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Cannabinoids are the individual chemical compounds in the marijuana plant, such as delta-9 THC, delta-8 THC, CBD, CBND, cannabielsoin (CBE), cannabicyclol (CBL), cannabitrol (CBT), and others

Another key player in -KG generation is the mitochondrial enzyme GDH1, which contributes to the accumulation of the subsequent metabolite fumarate

[1] If you experience persistent or concerning symptoms after starting B12 supplements, particularly skin changes or gastrointestinal issues, it is advisable to discuss these with your GP rather than assuming they are directly caused by vitamin excess

In a research setting, these compounds are supplied strictly as chemical reagents not as finished products intended for human use