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Appropriate choices for glucocorticoid replacement include 15 to 25 mg of oral hydrocortisone or 20 to 35 mg of cortisone acetate per day
And this involves hundreds of biochemical processes in the body
Its real, and its extremely common
Moreover, the specialized equipment required for pharmaceutical-grade SPPS represents a significant capital investment, and the expertise needed to operate and maintain these systems is concentrated in a relatively small number of contract manufacturing organizations globally
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