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found that non-diabetic human islets consist of three distinct populations of alpha-cells that differ based on proglucagon-derived peptides: one population that produces GLP-1, one that produces glucagon, and one that produces both GLP-1 and glucagon ( Figure 3 )
Monoclonal antibodies are commonly employed in high-sensitivity assays because they bind a single epitope with high precision, whereas polyclonal antibodies, which recognize multiple epitopes, may sometimes increase background noise
PubMed CrossRef Gejl M, Gjedde A., Egefjord L., et al
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