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Sinomenine is an active alkaloid from Sinomenium acutum , and its derivative facilitates interactions between nuclear receptor coactivator 4 (NCOA4) and FTH1, accelerating Fe 2+ release and ultimately promoting ferroptosis in colon cancer cells (Zhu et al., 2024)
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Bottom line While fatigue isnt the most common side effect of Wegovy, it can still happen, partially due to the medications impact on your appetite and gastrointestinal system
V., & Triplett, W
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