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People with a Medical or Surgical History of bariatric surgery or who have had part of their intestines removed, as well as those with absorptive disorders like inflammatory bowel disease, and those with duodenal ulcers
1,2 SORT: KEY RECOMMENDATIONS FOR PRACTICE Figure 1 In the United States and the United Kingdom, the prevalence of vitamin B 12 deficiency is approximately 6% in persons younger than 60 years, and nearly 20% in those older than 60 years
Intramuscular replacement therapy is indicated for patients with: Significant B12 deficiency (thresholds depend on local laboratory reference ranges) Neurological symptoms or signs Pernicious anaemia Malabsorption syndromes The standard UK regimen for patients without neurological involvement involves hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, followed by maintenance injections every 2-3 months (often 3-monthly)
Bacteriostatic water for injection can be used on medical equipment such as syringes and IV bags to help keep them sterile and free from contamination by bacteria or fungi
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