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* Correspondence: Pengbo Guo, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Most published evidence currently comes from laboratory and animal studies, with relatively few controlled human trials available

Older adults Vitamin B12 deficiency is Vegetarians and vegans Vitamin B12 mainly occurs in animal foods, so people who follow a plant-based diet have a In some cases, a doctor may recommend injections, but Vegetarians or vegans who are pregnant may If the infant is entirely breastfed, they may not consume enough vitamin B12

Our standard approach: Assess baseline health : Comprehensive bloodwork and licensed medical professional consultation to get a complete understanding of symptoms and treatment options