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The outcome was not a surprise after FDA briefing documents released on Monday took issue with NurOwns manufacturing plan and said the company failed to demonstrate substantial evidence of efficacy in its Biologics License Application

In a frequently cited 1999 rat wound study in the Journal of Investigative Dermatology, topical Thymosin Beta-4 was associated with a 42% increase in reepithelialization at four days and as much as 61% at seven days compared with saline controls, alongside increased angiogenesis

Eur J Plant Pathol 134

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