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While sitagliptin and exendin-4 significantly increase plasma insulin levels 5-min post injection, these levels are not significantly different from PBS control after 20 min, suggesting that the GLP-1 mediated reduction in intestinal-TG secretion is independent of the incretin effect
Jolivalt CG, Fineman M, Deacon CF, Carr RD, Calcutt NA (2011) GLP-1 signals via ERK in peripheral nerve and prevents nerve dysfunction in diabetic mice
Clinical Indications Musculoskeletal Applications Both BPC-157 and TB-500 have demonstrated significant therapeutic potential in addressing various musculoskeletal pathologies, representing some of the most promising clinical applications for these peptide therapeutics
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