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Neurovascular and repair endpoints include BBB leakage, tight-junction and pericyte coverage, perfusion, myeloid metabolic phenotype, and oligodendrocyte/white-matter integrity [14, 17, 18, 23, 25, 27,28,29]
Animal toxicology studies extended longer
GSH/GSSG is a reliable indicator of cellular redox status, and a chronic reduction in GSH/GSSG reflects a reduced antioxidant capacity and increased vulnerability to oxidative damage
It does not prove safety or effectiveness for any use that was not tested
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