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As expected, the engagement mode of Cagri with AMYRs is mainly conserved with that of rAmy and characterized by the formation of a bypass motif (residues S19 Cagri- P25 Cagri ) (Fig

A meta-analysis of 26 animal studies showed that GLP-1RAs improved learning and memory in rodent models of Alzheimers disease, possibly by decreasing brain levels of A-amyloid deposition and phosphorylated tau 33