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Beyond preclinical models, EGCg has shown significant promise in human clinical trials for severe viral inflammation

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Abnormalities of one-carbon metabolism in psychiatric disorders: study of methionine adenosyltransferase kinetics and lipid composition of erythrocyte membranes Biol Psychiatry 1986

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Additional preconception optimization includes folic acid supplementation (at least 400 mcg daily per CDC recommendations), screening for nutritional deficiencies that may have developed during rapid weight loss, and ensuring adequate protein intake

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