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Analysis of single-cell RNA sequencing Single-cell RNA sequencing (scRNA-seq) data (HRA000425) were downloaded from Genome Sequence Archive (SRA)-Human databases in China National Center for Bioinformation 16 , converted into FASTQ format using fasterq-dump software (sratoolkit 3.0.2, NCBI, NIH, Bethesda, MD, USA), converted into a matrix data file using Cell Ranger software version 3.0.2 (10xGenomics, Pleasanton, CA, USA), converted into Seurat objects using Seurat 5.0.1 software (Satija lab, Lower Manhattan, New York, NY, USA), and plotted for t -distributed stochastic neighbor embedding ( t -SNE) visualization

Lmna(K32) knock-in mouse model exhibited incomplete tissue maturation and severe metabolic defects, ultimately leading to premature death 36

It helps increase energy production, delay fatigue, and improve endurance by enhancing fat utilization during exercise

1 vol., Masson d., Paris), mesure de la contractilit musculaire (RUSSELL D