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Hyperglycemia potentiates collagen-induced platelet activation through mitochondrial superoxide overproduction
(2023) conducted a clinical trial on 26 psoriatic patients with chronic pruritus who were receiving thermal water hydrotherapy for 3 weeks and 18 psoriasis patients as controls who were receiving regular treatment with no hydrotherapy
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Prolonged homeostatic disruption impairs protein degradation processes, weakens molecular chaperone capacity, fosters inflammation, and incites mitochondrial damage through ROS/Ca 2+ , potentially affecting the follicular microenvironment and oocyte developmental potential [332, 333]
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