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Observational research has suggested a reduced risk of dementia among patients treated with GLP-1RAs, although prior clinical trials have been limited by small sample sizes and design constraints

Works Cited Once-Weekly Semaglutide in Adults With Alcohol Use Disorder JAMA Psychiatry GLP-1 Agonists and Substance-Use Hospitalizations JAMA Psychiatry Hype or Hope

The weight-loss effect of GLP-1RAs also benefits NASH improvement, by reducing appetite and increasing energy expenditure to promote weight loss, thereby indirectly ameliorating NASH