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Shots tend to work faster than oral pills because they bypass the digestive system

Keloid Senescent Fibroblast Elimination & SASP Suppression (Communications Biology, 2025) FOXO4-DRI Induces p53-pS15 Nuclear Exclusion and Apoptosis in Keloid Fibroblast Models A study published in Communications Biology (Nature Publishing Group, 2025) used single-cell RNA sequencing to characterise the senescent cell landscape in keloids pathological scars with tumour-like aggressiveness

However, no significant change in p-JNK protein level was observed in HUVECs (Figure 6)

Starting with a lower dose and gradually increasing helps minimize discomfort