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A 2024 systematic review and meta-analysis suggested NAC may be helpful as an add-on therapy for adults with moderate-to-severe OCD, but results have not been consistent across all psychiatric conditions or studies.33 Researchers are still working to determine which patients are most likely to respond and whether NAC's benefits are large enough to produce meaningful improvements in day-to-day functioning

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Maintenance Phase: Once the desired skin tone is achieved, maintenance doses (usually once every 2-4 weeks) help sustain results

therefore, some level of safety in human subjects can be assumed